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Singapore Clinical Trial: Phase 2b, Randomized, Double-Blind, Placebo-Controlled Clinical Trial, Preceded by a Single Ascending Dose Portion and a Phase 2 Open-Label Portion, to Evaluate the Safety and Efficacy of Oral Infigratinib in Infants and Young Children with Achondroplasia

Singapore, June 24 -- The Health Sciences Authority received information related to the study titled 'Phase 2b, Randomized, Double-Blind, Placebo-Controlled Clinical Trial, Preceded by a Single Ascend... Read More


Singapore Clinical Trial: A Phase 3 Open-label Randomized Study Assessing the Efficacy and Safety of RLY-2608 + Fulvestrant Versus Capivasertib + Fulvestrant as Treatment for PIK3CA-mutant Hormone Receptor Positive, Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Locally Advanced or Metastatic Breast Cancer Following Recurrence or Progression On or After Treatment with a CDK4/6 Inhibitor

Singapore, June 24 -- The Health Sciences Authority received information related to the study titled 'A Phase 3 Open-label Randomized Study Assessing the Efficacy and Safety of RLY-2608 + Fulvestrant ... Read More


Singapore Clinical Trial: A randomized, double-blind, placebo-controlled study to evaluate the effect of dupilumab on airway inflammation through assessments of mucus plugging and other lung imaging parameters in patients with chronic obstructive pulmonary disease

Singapore, June 24 -- The Health Sciences Authority received information related to the study titled 'A randomized, double-blind, placebo-controlled study to evaluate the effect of dupilumab on airway... Read More


Singapore Clinical Trial: CA088-1007: A Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safety of Arlocabtagene Autoleucel (BMS-986393), a GPRC5D-directed CAR-T Cell Therapy, Versus Standard Regimens in Adult Participants with Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

Singapore, June 24 -- The Health Sciences Authority received information related to the study titled 'CA088-1007: A Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safet... Read More


Singapore Clinical Trial: A Multinational, Multicenter, Prospective, Randomized, Controlled, Open-Label, Phase 3 Study of Lutetium-177 (177Lu) Rosopatamab Tetraxetan in Combination with Standard of Care Versus Standard of Care Alone in Patients with Prostate-Specific Membrane Antigen (PSMA) Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC) after Androgen Receptor Pathway Inhibitor (ARPI) Treatment

Singapore, June 24 -- The Health Sciences Authority received information related to the study titled 'A Multinational, Multicenter, Prospective, Randomized, Controlled, Open-Label, Phase 3 Study of Lu... Read More


Clinical Trial: A Phase II Trial for MOR Antagonism With Axelopran to Enhance Immunotherapy in Head and Neck Cancer

U.S., June 24 -- ClinicalTrials.gov registry received information related to the study (NCT07662720) titled 'A Phase II Trial for MOR Antagonism With Axelopran to Enhance Immunotherapy in Head and Nec... Read More


Clinical Trial: CD45RA-depleted DLI for the Treatment of Refractory/Persistent Viral Infections After Haploidentical Transplantation

U.S., June 24 -- ClinicalTrials.gov registry received information related to the study (NCT07662369) titled 'CD45RA-depleted DLI for the Treatment of Refractory/Persistent Viral Infections After Haplo... Read More


Clinical Trial: Timing of Recruitment Maneuver in Robotic Prostate Surgery

U.S., June 24 -- ClinicalTrials.gov registry received information related to the study (NCT07662642) titled 'Timing of Recruitment Maneuver in Robotic Prostate Surgery' on June 11. Brief Summary: Rob... Read More


Clinical Trial: Remimazolam-Flumazenil Versus Sevoflurane for Hysteroscopic Day Surgery

U.S., June 24 -- ClinicalTrials.gov registry received information related to the study (NCT07663877) titled 'Remimazolam-Flumazenil Versus Sevoflurane for Hysteroscopic Day Surgery' on June 15. Brief... Read More


Clinical Trial: Finding Immune Nascent Type 1 Diabetes

U.S., June 24 -- ClinicalTrials.gov registry received information related to the study (NCT07663136) titled 'Finding Immune Nascent Type 1 Diabetes' on June 17. Brief Summary: The goal of this clinic... Read More